NEUROSCIENTIST · PHYSICIAN-SCIENTIST

Seunghwan Choi

Seunghwan Choi (최승환)

Neuroscientist.
Physician-scientist.
Bridging clinical insights and science to conquer disease.

Curriculum Vitae
Two-photon imaging

Watching the many players of the brain — neurons, astrocytes, cerebrospinal fluid, blood vessels and immune cells — is my great pleasure.

In vivo two-photon microscopy in the living mouse, where they can be seen at work in the brain.


Curriculum Vitae

Education
2025
Ph.D. in Medicine
Kyung Hee University
  • Degree Recipient Representative & Outstanding Academic Achievement
  • Advisor: Sun Kwang Kim, KMD, PhD
  • Thesis: “Neuromodulation Strategies Targeting CSF Circulation and Astrocytic Calcium Signaling”
2021
Doctor of Medicine (MD)
Kyung Hee University
  • Graduated Cum Laude
2019
M.S. in Medicine
Kyung Hee University
  • Best Research Award
  • Advisor: Sun Kwang Kim, KMD, PhD & Byung-Il Min, MD, KMD, PhD
2017
Doctor of Korean Medicine (KMD)
Kyung Hee University
  • 한의사, Professional undergraduate degree in complementary and alternative medicine
Research Experience
2026 – Present
Visiting Researcher
University of Yamanashi, Japan
Host: Shuichi Koizumi, PhD
2025 – Present
Research Professor
Kyung Hee University, Korea
2021 – 2024
Technical Research Personnel
Kyung Hee University, Korea
박사과정 전문연구요원, Designated by the Korean government for advanced scientific research (Substitutive Military Service)
2014 – 2015
Visiting Researcher
National Institute for Physiological Sciences (NIPS), Japan
Host: Hidemasa Furue, PhD
Awards & Honors
Young Investigator Award in Basic Medical Science — Korean Medical Association
2025
Outstanding Academic Achievement Award — Kyung Hee University
2025
Lab Visit Travel Bursary — ISCBFM (Visit to MGH, USA)
2025
Young Investigator Best Award — Korean Physiology Society
2024
Young Scientist Award — ICMART
2024
Best Poster Award — Korea Society for Therapeutic Ultrasound
2024
The Health Fellowship Foundation Scholarship
2023
Best Research Award — Kyung Hee University
2019
KIOM-URP Gold Prize — Korea Institute of Oriental Medicine
2015
Publications
  1. Seunghwan Choi, Jae Hyun Park, Chan Su Kim, Sun Kwang Kim, “Proteomic analysis of transcutaneous auricular vagus nerve stimulation induced cognitive restoration in a mouse model of vascular cognitive impairment”, Molecular Brain, 2026.
  2. Seunghwan Choi, Hyunjin Shin, Seon Young Hyun, Geehoon Chung, Sun Kwang Kim, “STIM1-dependent calcium signaling in astrocytes controls glutamate accumulation and ischemic brain injury during acute stroke in mice”, Glia, 2026.
  3. Hyunjin Shin, Seunghwan Choi, Geehoon Chung, Sun Kwang Kim, “Analgesic effects of transcutaneous auricular vagus nerve stimulation on partial sciatic nerve ligation-induced neuropathic pain in mice via serotonergic pathways”, Molecular Brain, 2025.
  4. Seunghwan Choi, In Seon Baek, Kyungjoon Lee, Sun Kwang Kim, “Low-Frequency Auricular Vagus Nerve Stimulation Facilitates Cerebrospinal Fluid Influx by Promoting Vasomotion”, The Korean Journal of Physiology & Pharmacology, 2025.
  5. Seunghwan Choi, Jeungeun Kum, Seon Young Hyun, Tae Young Park, Hyungmin Kim, Sun Kwang Kim, Jaeho Kim, “Transcranial Focused Ultrasound Stimulation Enhances Cerebrospinal Fluid Movement: Real-Time In Vivo Two-Photon and Widefield Imaging Evidence”, Brain Stimulation, 2024.
  6. In Seon Baek, Seunghwan Choi, Heera Yoon, Geehoon Chung, Sun Kwang Kim, “Analgesic effect of auricular vagus nerve stimulation on oxaliplatin-induced peripheral neuropathic pain in a rodent model”, Experimental Neurobiology, 2024.
  7. Dong Cheol Jang, Seunghwan Choi, Geehoon Chung, Sun Kwang Kim, “Global cerebral ischemia induced depression accompanies alteration of neuronal excitability in the infralimbic cortex layer 2/3 pyramidal neurons”, Experimental Neurobiology, 2023.
  8. Seunghwan Choi, Dong Cheol Jang, Geehoon Chung, Sun Kwang Kim, “Transcutaneous auricular vagus nerve stimulation enhances cerebrospinal fluid circulation and restores cognitive function in the rodent model of vascular cognitive impairment”, Cells, 2022.
  9. Seunghwan Choi, Hyeon Kyeong Chae, Ho Heo, Dae-Hyun Hahm, Woojin Kim, Sun Kwang Kim, “Analgesic Effect of Melittin on Oxaliplatin-Induced Peripheral Neuropathy in Rats”, Toxins, 2019.
  10. Woojin Kim, Yeongu Chung, Seunghwan Choi, Byung-Il Min, Sun Kwang Kim, “Duloxetine Protects against Oxaliplatin-Induced Neuropathic Pain and Spinal Neuron Hyperexcitability in Rodents”, International Journal of Molecular Sciences, 2017.
  11. Seunghwan Choi, Akihiro Yamada, Woojin Kim, Sun Kwang Kim, Hidemasa Furue, “Noradrenergic inhibition of spinal hyperexcitation elicited by cutaneous cold stimuli in rats with oxaliplatin-induced allodynia: electrophysiological and behavioral assessments”, Journal of Physiological Sciences, 2017.
Patents

KR/JP Patent: Stimulus applying device


Academic

Academic roots & interests

I have been trained under the mentorship of Dr. Sun Kwang Kim at Kyung Hee University, Korea for several years starting from my undergraduate. I am proud of being a part of the great neuroscience academic lineage in Korea and Japan.

On the basis of their scientific contribution, I have interests in in vivo two-photon imaging, astrocyte-centered neurobiology, stroke, chronic pain, and neuromodulation (acupuncture, transcutaneous electrical stimulation, vagus nerve stimulation, and focused ultrasound stimulation).

In vivo two-photon imaging Astrocyte-centered neurobiology Stroke Chronic pain Neuromodulation Acupuncture Transcutaneous electrical stimulation Vagus nerve stimulation Focused ultrasound stimulation

Motivation

What I want to do as a scientist

My critical mind as a scientist is that science has a great power of problem-solving potential in the real world. In my undergraduate and master’s courses, neuropathic pain was my main interest. That was from my father’s uncontrolled neuropathic pain in his face.

At the starting point of my PhD course, my grandmother had a stroke attack. Although she survived, she had suffered from cognitive impairment (vascular dementia). That was my motivation for research in stroke and vascular cognitive impairment (at that time, she had severe cognitive impairment and behavioral and psychological symptoms of dementia).

Again, I believe that science has a power to solve the problems.

Read the interview

Timeline

Along the way

2014 First surgical pain model January 2014
Performing an experimental surgery in the laboratory
My first attempt at a surgical pain model, as a research intern at Seoul National University.
2015 Gold Prize, KIOM undergraduate research program
Presenting research from the podium
The Korea Institute of Oriental Medicine undergraduate research program (KIOM-URP). Read the news ↗
2016 16th World Congress on Pain September 2016
Poster presentation at the 16th World Congress on Pain
My first poster presentation.
Yokohama, Japan, 26–30 September 2016.
2019 White coat ceremony February 2019
At the white coat ceremony in medical school
At the white coat ceremony in medical school, with the woman who is now my wife.
2022 Everyday work in the laboratory September 2022
At the desk in the laboratory office
Most of a PhD happens here — at the desk, between experiments.
2022 Basic military training December 2022
With my father at the Korea Army Training Center
With my father (he served as an army officer for many years) at the Korea Army Training Center, entering the technical research service.
2024 End of the technical research service August 2024
Commemorative plaque made by the laboratory members
A plaque the lab members made to mark the completion of my technical research service.
2024 Young Scientist Award, ICMART September 2024
Award lecture at the 37th ICMART World Congress, Jeju
37th ICMART World Congress, Jeju. Read more ↗
2024 Young Investigator Best Award, Korean Physiology Society November 2024
Young investigator oral presentation at the Korean Physiological Society
76th Annual Meeting of the Korean Physiological Society.
2024 Wedding November 2024
Wedding ceremony in the chapel
The most important moment of my life. My wife and I met in medical school and married after eight years together.
2025 Lab visit to Massachusetts General Hospital March 2025
In front of Massachusetts General Hospital, Boston
My first visit to Boston (Host: David Y Chung, MD, PhD)
The words of John Collins Warren inscribed in the Ether Dome felt as though they were addressed to me.
“The student who from distant lands or in distant ages may visit this spot will view it with increased interest, as he remembers that here was first demonstrated one of the most glorious truths of science.”
2025 Young Investigator Award in Basic Medical Science April 2025
Award plaque from the Korean Medical Association
The 32nd award, presented at the 77th General Assembly of the Korean Medical Association. Read the news ↗
2025 PhD defense June 2025
PhD defense presentation
Concluding four and a half years of doctoral work.
2025 PhD conferred — degree recipient representative August 2025
Receiving the doctoral diploma on stage
Receiving the diploma as the representative of the graduating class.
2026 Visiting Scholar, University of Yamanashi May 2026
Research proposal seminar at the University of Yamanashi
Starting as a visiting scholar in the Department of Pharmacology, Faculty of Medicine — the research proposal seminar on my first days there.

Identity

Favorites

Idyllic · Serene · Aesthetic · Still · Contemplative · Intimate

Nine things I keep coming back to, outside the laboratory. They are the same instincts I bring to research: look closely, wait for the moment, and keep the people around you close.

Peaceful nature, San Diego
01
Peaceful nature
A walk between conference sessions in San Diego.
A letter from a colleague’s daughter
02
Relationship
A letter from my lab mate's daughter: “Congratulations on your PhD”
The Louvre museum
03
Pursuing visual aesthetics
The Louvre museum. Looking closely is the same habit in a gallery and under the microscope.
Discussion with colleagues
04
Discussion & problem-solving
With colleagues. Most of my projects began as a question asked at someone else’s desk.
Taking photographs
05
Taking photographs
Framing, waiting, and deciding what to leave out. Happy to capture the moment of friends.
Photographs with narratives
06
Photographs with narratives
At Dune du Pilat, France
Also love the work of Dr. Jeon — jmong.net ↗
07
Training
Weight training with consistency
Teamwork

Me within a team

As a member, colleague and friend in the research group, I have sought to cultivate a strong sense of belonging, solidarity, and connection within the team, thereby contributing to stronger teamwork.
Lab members with a congratulatory graduation banner
Graduation with members
Group photo with the laboratory members
Lab photo